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1

The application of systems biology to drug discovery

Carolyn R Cho, Mark Labow, Mischa Reinhardt, Jan van Oostrum, Manuel C Peitsch

Journal:

Current Opinion in Chemical Biology

Year:

2006

Language:

english

File:

PDF, 547 KB

english, 2006

2

Towards high performance two-dimensional gel electrophoresis using ultrazoom gels

Sjouke Hoving, Hans Voshol, Jan van Oostrum

Journal:

ELECTROPHORESIS

Year:

2000

Language:

english

File:

PDF, 300 KB

english, 2000

3

Protein purification by Off-Gel electrophoresis

Alexandra Ros, Michel Faupel, Hervé Mees, Jan van Oostrum, Rosaria Ferrigno, Frédéric Reymond, Philippe Michel, Joël S. Rossier, Hubert H. Girault

Journal:

Year:

2002

Language:

english

File:

PDF, 1.44 MB

english, 2002

4

Preparative two-dimensional gel electrophoresis at alkaline pH using narrow range immobilized pH gradients

Sjouke Hoving, Bertran Gerrits, Hans Voshol, Dieter Müller, Rosalinda C. Roberts, Jan van Oostrum

Journal:

Year:

2002

Language:

english

File:

PDF, 1.19 MB

english, 2002

5

Microfabricated polymer injector for direct mass spectrometry coupling

Véronique Gobry, Jan van Oostrum, Marco Martinelli, Tatiana C. Rohner, Frédéric Reymond, Joël S. Rossier, Hubert H. Girault

Journal:

Year:

2002

Language:

english

File:

PDF, 164 KB

english, 2002

6

Post-translational modification detection using metastable ions in reflector matrix-assisted laser desorption/ionization-time of flight mass spectrometry

Urs Wirth, Dieter Müller, Patrick Schindler, Joerg Lange, Jan van Oostrum

Journal:

Year:

2002

Language:

english

File:

PDF, 197 KB

english, 2002

7

Site-specific analysis of the N-glycans on murine polymeric immunoglobulin A using liquid chromatography/electrospray mass spectrometry

Eddy A. Kragten, Aldert A. Bergwerff, Jan van Oostrum, Dieter R. Müller, Wilhelm J. Richter

Journal:

Journal of Mass Spectrometry

Year:

1995

Language:

english

File:

PDF, 670 KB

english, 1995

8

Tracing pathway activities with kinase inhibitors and reverse phase protein arrays

Jan van Oostrum, Claudio Calonder, Daniel Rechsteiner, Markus Ehrat, Jürgen Mestan, Doriano Fabbro, Hans Voshol

Journal:

PROTEOMICS - Clinical Applications

Year:

2009

Language:

english

File:

PDF, 608 KB

english, 2009

9

Effects of verapamil on the pharmacokinetics of daunomycin in the rat

Kees Nooter, Robert Oostrum, Jan Deurloo

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1987

Language:

english

File:

PDF, 269 KB

english, 1987

10

Repeated daunomycin administration in rats

Kees Nooter, Pieter Sonneveld, Jan Deurloo, Robert Oostrum, Frank Schultz, Anton Martens, Anton Hagenbeek

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1984

Language:

english

File:

PDF, 280 KB

english, 1984

11

Variation in N-linked carbohydrate chains in different batches of two chimeric monoclonal IgG1 antibodies produced by different murine SP2/0 transfectoma cell subclones

Aldert A. Bergwerff, Corné J. M. Stroop, Brendan Murray, Anke-Peggy Holtorf, Gerd Pluschke, Jan Oostrum, Johannis P. Kamerling, Johannes F. G. Vliegenthart

Journal:

Glycoconjugate Journal

Year:

1995

Language:

english

File:

PDF, 1.36 MB

english, 1995

12

Antibody-based proteomics : Analysis of signaling networks using reverse protein arrays

Hans Voshol, Markus Ehrat, Jens Traenkle, Eric Bertrand, Jan van Oostrum

Journal:

Year:

2009

Language:

english

File:

PDF, 482 KB

english, 2009

13

Neuroproteomics: Expression Profiling of the Brain's Proteomes in Health and Disease

Sandra I. Kim, Hans Voshol, Jan van Oostrum, Terri G. Hastings, Michael Cascio, Marc J. Glucksman

Journal:

Neurochemical Research

Year:

2004

Language:

english

File:

PDF, 214 KB

english, 2004

14

Op18/stathmin caps a kinked protofilament-like tubulin tetramer

Steinmetz, Michel O., Kammerer, Richard A., Jahnke, Wolfgang, Goldie, Kenneth N., Lustig, Ariel, van Oostrum, Jan

Journal:

The EMBO Journal

Year:

2000

Language:

english

File:

PDF, 711 KB

english, 2000

15

Interpretation of electron micrographs of adenovirus hexon arrays using a crystallographic molecular model

Jan van Oostrum, P.R. Smith, Manijeh Mohraz, Roger M. Burnett

Journal:

Journal of Ultrastructure and Molecular Structure Research

Year:

1986

Language:

english

File:

PDF, 5.37 MB

english, 1986

16

Fewer intensive care unit refusals and a higher capacity utilization by using a cyclic surgical case schedule

Mark Van Houdenhoven, Jeroen M. van Oostrum, Gerhard Wullink, Erwin Hans, Johann L. Hurink, Jan Bakker, Geert Kazemier

Journal:

Journal of Critical Care

Year:

2008

Language:

english

File:

PDF, 258 KB

english, 2008

17

Identification of Manα1-3Manα1-2Man and Man-linked phosphate on O-mannosylated recombinant leech-derived tryptase inhibitor produced by Saccharomyces cerevisiae and determination of the solution conformation of the mannosylated polypeptide

Aldert A. Bergwerff, Wilhelm Stark, Gabriele Fendrich, René Knecht, Marcel J. J. Blommers, Walter Maerki, Eddy A. Kragten, Jan van Oostrum

Journal:

Year:

1998

Language:

english

File:

PDF, 678 KB

english, 1998

18

Primary structure of N-linked carbohydrate chains of a human chimeric plasminogen activator K2tu-PA expressed in Chinese hamster ovary cells

Aldert A. BERGWERFF, Jan van OOSTRUM, Fred A. M. ASSELBERGS, Rolf BÜRGI, Cornelis H. HOKKE, Johannis P. KAMERLING, Johannes F. G. VLIEGENTHART

Journal:

Year:

1993

Language:

english

File:

PDF, 1.62 MB

english, 1993

19

The Major N-Linked Carbohydrate Chains from Human Urokinase : The Occurrence of 4-O-sulfated, (α2-6)-sialylated or (α1-3)-fucosylated N-acetylgalactosamine(β1-4)-N-acetylglucosamine Elements

Aldert A. Bergwerff, Jan Van Oostrum, Johannis P. Kamerling, Johannes F. G. Vliegenthart

Journal:

Year:

1995

Language:

english

File:

PDF, 1.08 MB

english, 1995

20

Isolation and crystallization of λ exonuclease

Jan van Oostrum, Janice L. White, Roger M. Burnett

Journal:

Archives of Biochemistry and Biophysics

Year:

1985

Language:

english

File:

PDF, 745 KB

english, 1985

21

Mode of action of the lanthionine-containing peptide antibiotics duramycin, duramycin B and C, and cinnamycin as indirect inhibitors of phospholipase A2

Fritz Märki, Elvira Hänni, Andreas Fredenhagen, Jan van Oostrum

Journal:

Biochemical Pharmacology

Year:

1991

Language:

english

File:

PDF, 746 KB

english, 1991

22

Sialylated carbohydrate chains of recombinant human glycoproteins expressed in Chinese hamster ovary cells contain traces of N-glycolylneuraminic acid

Cornelis H. Hokke, Aldert A. Bergwerff, Gijs W.K. van Dedem, Jan van Oostrum, Johannis P. Kamerling, Johannis F.G. Vliegenthart

Journal:

Year:

1990

Language:

english

File:

PDF, 748 KB

english, 1990

23

Human urokinase contains Ga1NAcβ(1-4)[Fucα(1-3)]G1cNAcβ(1-2) as a novel terminal element in N-linked carbohydrate chains

Aldert A. Bergweff, Jane E. Thomas-Oates, Jan van Oostrum, Johannis P. Kamerling, Johannes F.G. Vliegenthart

Journal:

Year:

1992

Language:

english

File:

PDF, 563 KB

english, 1992

24

Unique chemical reactivity of His-21 of CRM-197, a mutated diphtheria toxin

Jui-Yoa Chang, Ueli Ramseier, Tom Hawthorne, Terry O'Reilly, Jan van Oostrum

Journal:

Year:

1998

Language:

english

File:

PDF, 128 KB

english, 1998

25

Progress in Understanding Adenovirus Architecture

Burnett, Roger M., van Oostrum, Jan, Roberts, Michael M.

Journal:

Biophysical Journal

Year:

1986

Language:

english

File:

PDF, 407 KB

english, 1986

26

Architecture of the Adenovirus Capsid

JAN van OOSTRUM, ROGER M. BURNETT

Journal:

Annals of the New York Academy of Sciences

Year:

1984

Language:

english

File:

PDF, 875 KB

english, 1984

27

The structure of murine interleukin-1 β at 2.8 Å resolution

Jan Van Oostrum, John P. Priestle, Markus G. Grutter, Albert Schmitz

Journal:

Journal of Structural Biology

Year:

1991

Language:

english

File:

PDF, 785 KB

english, 1991

28

X-ray Diffraction Studies on Adenovirus Type 5 Hexon

MICHAEL M. ROBERTS, JAN VAN OOSTRUM, ROGER M. BURNETT

Journal:

Annals of the New York Academy of Sciences

Year:

1987

Language:

english

File:

PDF, 521 KB

english, 1987

29

The Vertex Morphology of the Adenovirus Capsid

JAN VAN OOSTRUM, P. R. SMITH, Manijeh Mohraz, ROGER M. BURNETT

Journal:

Annals of the New York Academy of Sciences

Year:

1987

Language:

english

File:

PDF, 191 KB

english, 1987

30

Targeted proteomics strategy applied to biomarker evaluation

Kim, Yeoun Jin, Gallien, Sebastien, van Oostrum, Jan, Domon, Bruno

Journal:

PROTEOMICS - Clinical Applications

Year:

2013

Language:

english

File:

PDF, 421 KB

english, 2013

31

The structure of the adenovirus capsid

van Oostrum, Jan, Smith, P.R., Mohraz, Manijeh, Burnett, Roger M.

Journal:

Journal of Molecular Biology

Year:

1987

Language:

english

File:

PDF, 7.32 MB

english, 1987

32

Evaluation of Biomarker Discovery Approaches to Detect Protein Biomarkers of Acute Renal Allograft Rejection †

Voshol, Hans, Brendlen, Nathalie, Müller, Dieter, Inverardi, Bruno, Augustin, Angélique, Pally, Charles, Wieczorek, Grazyna, Morris, Randall E., Raulf, Friedrich, van Oostrum, Jan

Journal:

Journal of Proteome Research

Year:

2005

Language:

english

File:

PDF, 406 KB

english, 2005

33

Identification of a reactive lysyl residue (Lys103) of recombinant human interleukin-1.beta.. Mechanism of its reactivity and implication of its functional role in receptor binding

Chang, Jui Yoa, Ngai, Philip K., Priestle, John P., Joss, Urs, Vosbeck, Klaus D., Van Oostrum, Jan

Journal:

Year:

1992

Language:

english

File:

PDF, 1.11 MB

english, 1992

34

Neoepitope Immunoassay: An Assay for Human Interleukin 1β Based on an Antibody Induced Conformational Change

Towbin, Harry, Erard, François, van Oostrum, Jan, Schmitz, Albert, Rordorf, Christiane

Journal:

Journal of Immunoassay

Year:

1996

Language:

english

File:

PDF, 576 KB

english, 1996

35

Screening protein isoforms predictive for cancer using immunoaffinity capture and fast LC-MS in PRM mode

Lesur, Antoine, Ancheva, Lina, Kim, Yeoun Jin, Berchem, Guy, van Oostrum, Jan, Domon, Bruno

Journal:

PROTEOMICS - Clinical Applications

Year:

2015

Language:

english

File:

PDF, 930 KB

english, 2015

36

Proteomics in the Discovery of New Therapeutic Targets for Psychiatric Disease

Voshol, Hans, Glucksman, Marc, Oostrum, Jan

Journal:

Current Molecular Medicine

Year:

2003

Language:

english

File:

PDF, 280 KB

english, 2003

37

A Simulation Model for Determining the Optimal Size of Emergency Teams on Call in the Operating Room at Night

van Oostrum, Jeroen M., Van Houdenhoven, Mark, Vrielink, Manon M. J., Klein, Jan, Hans, Erwin W., Klimek, Markus, Wullink, Gerhard, Steyerberg, Ewout W., Kazemier, Geert

Journal:

Anesthesia & Analgesia

Year:

2008

Language:

english

File:

PDF, 512 KB

english, 2008

38

Complexity reduction of clinical samples for routine mass spectrometric analysis

Mesmin, Cédric, van Oostrum, Jan, Domon, Bruno

Journal:

PROTEOMICS - Clinical Applications

Year:

2016

Language:

english

File:

PDF, 468 KB

english, 2016

39

The Human Genome: Proteomics

Van Oostrum, Jan, Voshol, Hans

Journal:

American Journal of Psychiatry

Year:

2002

Language:

english

File:

PDF, 71 KB

english, 2002

40

Predictors for successful PBSC collection on the fourth day of G-CSF-induced mobilization in allogeneic stem cell donors

van Oostrum, Anja, Zwaginga, Jaap Jan, Croockewit, Sandra, Overdevest, Jacqueline, Fechter, Mirjam, Ruiterkamp, Bart, Brand, Anneke, Netelenbos, Tanja

Journal:

Journal of Clinical Apheresis

Year:

2017

Language:

english

File:

PDF, 710 KB

english, 2017

41

Targeted proteomics identifies proteomic signatures in liquid-biopsies of the endometrium to diagnose endometrial cancer and assist in the prediction of the optimal surgical treatment

Martinez, Elena, Lesur, Antoine, Devis, Laura, Cabrera, Silvia, Matias-Guiu, Xavier, Hirschfeld, Marc, Asberger, Jasmin, van Oostrum, Jan, Casares de Cal, María de los Ángeles, Gómez-Tato, Antonio, Re

Journal:

Clinical Cancer Research

Year:

2017

Language:

english

File:

PDF, 947 KB

english, 2017

42

Advances in endometrial cancer protein biomarkers for use in the clinic

Martinez-Garcia, Elena, Lopez-Gil, Carlos, Campoy, Irene, Vallve, Julia, Coll, Eva, Cabrera, Silvia, Ramon Y Cajal, Santiago, Matias-Guiu, Xavier, Van Oostrum, Jan, Reventos, Jaume, Gil-Moreno, Antoni

Journal:

Expert Review of Proteomics

Year:

2017

Language:

english

File:

PDF, 1.68 MB

english, 2017

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